Genesis Biosciences recently collaborated with the University of Huddersfield on a study focusing on the effectiveness of Bacillus-based probiotic cleaners in mitigating dry biofilms that can be present on hospital surfaces.

The challenge

Surfaces in hospital and clinical settings can harbour microbial pathogens present in dry biofilms that contribute to the risk of infections and antimicrobial resistance.  The study aimed to investigate the use of Bacillus-based probiotic cleaners as a potential way to reduce surface pathogen biofilm formation.

About the study

The study focused on the effectiveness of Genesis Biosciences probiotic cleaners containing beneficial Bacillus strains, in mitigating dry biofilms that can be prevalent on a multitude of surfaces within the clinical setting. The primary objective was to understand how these cleansers could serve as a proactive measure against healthcare-associated infections and antimicrobial resistance (AMR).

The results demonstrated the potential for Genesis’s probiotic cleaners to prevent and reduce the formation of dry biofilms, achieving an impressive reduction of over 97.7%. This efficacy spanned diverse surfaces, including steel, melamine, and ceramic, countering common pathogens like Escherichia coli and Staphylococcus aureus.

Kate Ledwoch, Senior Scientist at the Genesis Biosciences UK laboratory


For a detailed insight into the findings and methodologies employed, the resulting paper offers a comprehensive overview of the study. This important research collaboration showcases the capability of Bacillus spp. to successfully colonise dry hard surfaces and effectively outcompete relevant pathogens, underlining the potential application of probiotic cleaning in healthcare settings, helping to contribute to a safer healthcare environment.

Read the study

This publication was a collaboration between Genesis Biosciences and the University of Huddersfield and represents an essential update to existing research and work, driven by the goal of fundamentally enhancing hospital safety and hygiene. 

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